The demand for innovative RNA synthesis technologies has surged in recent years, particularly due to the emergence of RNA-based therapeutic strategies such as vaccines. Circular RNAs (circRNAs) are attracting significant attention for their stability and potential therapeutic applications. Unlike linear RNAs, circRNAs are resistant to exonuclease degradation, displaying unique structural...
Gene fusions, the result of chromosomal rearrangements such as translocations, inversions, deletions, or insertions, are integral in cancer biology. These rearrangements create chimeric genes, which have strategic importance in precision medicine. They serve as therapeutic biomarkers, aiding in the diagnosis, prognosis, and advancement of targeted therapies.
However, understanding the...